Figure 5: Synthesis of cassette D.

Reagents and conditions: (a) AuCl3 (7 mol%), AgOTf (7 mol%), CH2Cl2, 4 Å MS powder, 25 °C, 2 h; 70% for 19 and 75% for 20. (b) Py·HF, THF:Py (5:1), 0 °C→25 °C, 4 h, 95%.

Reagents and conditions: (a) AuCl3 (7 mol%), AgOTf (7 mol%), CH2Cl2, 4 Å MS powder, 25 °C, 2 h; 70% for 19 and 75% for 20. (b) Py·HF, THF:Py (5:1), 0 °C→25 °C, 4 h, 95%.