Table 3 Physiological properties of isolated EDLs from aged WT, mdx and dKO mice.
From: Evidence for ACTN3 as a genetic modifier of Duchenne muscular dystrophy
Parameter | WT | mdx | dKO |
---|---|---|---|
EC50 (Hz) | 50.2±0.7 | 60.9±0.3* | 57.0±1.6* |
Hill co-efficient | 3.8±0.2 | 4.3±0.2 | 4.1±0.3 |
Twitch time to peak (ms) | 24.6±0.6 | 18.0±0.7* | 18.9±2.5* |
Twitch half-relax time (ms) | 17.2±2.4 | 10.2±0.8* | 18.2±6.6† |