Figure 1: Cerebral microvasculature defects in Glut1 DS. | Nature Communications

Figure 1: Cerebral microvasculature defects in Glut1 DS.

From: Brain microvasculature defects and Glut1 deficiency syndrome averted by early repletion of the glucose transporter-1 protein

Figure 1

(a) Thalamic sections of Glut1 DS model mice and littermate controls stained with labelled lectin reveal cerebral angiogenesis defects and diminution of the microvasculature of mutants at 8 and 20 weeks of life. Graphs quantifying (b) aggregate cerebral capillary length, (c) mean vessel size and (d) average capillary branches in the mutants and controls illustrate the diminished size of the microvasculature in adult Glut1 DS mice. ***, P<0.001, t-test, n≥9 regions from each of N≥3 mice of each genotype examined.

Back to article page