Figure 5: F-VHHs make direct contacts with residues on two neighbouring protomers of prefusion F. | Nature Communications

Figure 5: F-VHHs make direct contacts with residues on two neighbouring protomers of prefusion F.

From: Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state

Figure 5

Close-up of the CDR3 and CDR2 from (a) F-VHH-4 and (b) F-VHH-L66 bound to prefusion F. CDR2 and CDR3 are shown as tubes with the N- and C-termini labelled. Side-chains and main-chain involved in hydrogen bonding are shown as sticks, with hydrogen bonds depicted as black dotted lines. Residues of the F protein are labelled.

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