Figure 5: Reduced brush border loss and NGAL excretion in fructokinase knockout mice undergoing iAKI.
From: Protective role of fructokinase blockade in the pathogenesis of acute kidney injury in mice
(a) Representative images of ACE staining—brush border marker—of sham operation and mice (wild type (WT) or fructokinase deficient (KHK-A/C KO) undergoing iAKI). (b) Intensity quantitation of ACE staining in the same groups of animals. (c) Urinary NGAL levels in the same groups of animals. Data indicate mean±s.e.m. *P<0.05, **P<0.01 and ***P<0.001 versus baseline or within the same group. n=5–9 animals per group with two different studies ###P<0.001, ##P<0.01. Statistical analysis was performed with ANOVA with ad hoc analysis by Bonferroni's method to compare all columns. Scale bar: black 500 μm, red 100 μm.
