Table 1 In vitro neutralization of influenza B viruses by 46B8.
From: A broadly protective therapeutic antibody against influenza B virus with two mechanisms of action
Influenza B Strain | Lineage | IC 50 (nM) | 95% CI (nM) |
---|---|---|---|
B/Phuket/3073/2013 | Yamagata | 0.73 | 0.65–0.82 |
B/Massachusetts/2/2012 | Yamagata | 0.69 | 0.61–0.78 |
B/Wisconsin/1/2010 | Yamagata | 0.64 | 0.53–0.76 |
B/Bangladesh/3333/2007 | Yamagata | 0.75 | 0.62–0.92 |
B/Victoria/504/2000 | Yamagata | 0.67 | 0.62–0.73 |
B/Brisbane/60/2008 | Victoria | 0.86 | 0.72–1.04 |
B/Malaysia/2506/2004 | Victoria | 0.58 | 0.36–0.91 |
B/Russia/1/1969 | Ancestral | 0.73 | 0.61–0.86 |
B/Massachusetts/3/1966 | Ancestral | 0.80 | 0.65–0.98 |
B/Maryland/1/1959 | Ancestral | 0.95 | 0.71–1.26 |
B/Lee/10/1940 | Ancestral | 0.68 | 0.55–0.85 |