Table 1 Sample size, age and PSA levels of subjects included in discovery GWAS and replication studies.

From: Genome-wide association study of prostate-specific antigen levels identifies novel loci independent of prostate cancer

Study population

N

Mean age * (s.d.)

Median PSA * (MAD)

Discovery

 KP non-Hispanic White non-cases

28,503

68.8 (10.2)

1.5 (1.2)

Replication

 KP Latino non-cases

2,716

65.6 (11.2)

1.4 (1.2)

 KP East Asian non-cases

2,518

66.0 (10.5)

1.5 (1.2)

 KP African American non-cases

1,585

66.1 (9.3)

1.4 (1.2)

 KP non-Hispanic White Cases

5,006

60.8 (7.6)

2.7 (2.2)

 Vanderbilt White non-cases

1,411

59.7 (11.4)

0.8 (3.5)

 PEGASUS White non-cases

2,833

63.3 (5.1)

1.1 (0.89)

 Malmö White non-cases

1,359

61.4 (6.3)

1.0 (0.70)

  1. GWAS, genome-wide association study; KP, Kaiser Permanente; MAD, median absolute deviation; PSA, prostate-specific antigen.
  2. KP non-Hispanic white non-cases are included in the discovery GWAS. The other seven populations are included in the replication.
  3. *For KP non-cases, age and median are of their most recent PSA measurement. For KP cases, age and median are of their oldest PSA measurement, required to be at least two years prior to diagnosis.
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