Figure 7: Different conformational states of the C-edge.
From: C-edge loops of arrestin function as a membrane anchor
(a) Superposition of sampled MD frame obtained based on the best fitting to the crystallized Ops*arrestin-1 complex (PDB ID: 4ZWJ) to the ‘α-conformer’ seen in the crystal structure of arrestin-1 reported by Hirsch et al. (PDB ID: 1CF1, molecule A). (b) Sampled MD frame alone. (c) Crystallized ‘α-conformer’ alone. The averaged layer of phosphate atoms (P) and carbon 5 (C5) of lipids are simulation-based coordinates and are indicated by tan and red lines, respectively.
