Figure 9: Simulations comparing the purified and unpurified models. | Nature Communications

Figure 9: Simulations comparing the purified and unpurified models.

From: Compiler-aided systematic construction of large-scale DNA strand displacement circuits using unpurified components

Figure 9

(a) Simulations of the rule 110–124 circuit using the previously developed model for purified seesaw circuits, predicting that the circuit should yield desired outputs in roughly 8 h (shown as dotted lines) and the undesired reactions will take over in 24 h. (b) Simulations using the new model for unpurified seesaw circuits, predicting that the circuit should yield desired outputs in roughly 24 h. kf=2 × 106 M−1 s−1, ks=5 × 104 M−1 s−1, kl=10 M−1 s−1, krf=26 s−1, krs=1.3 s−1. 1 × =100 nM.

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