Table 1 Selected genes with enhancer-associated insertions in their insulated neighbourhoods.
From: Small genomic insertions form enhancers that misregulate oncogenes
Tumour type | Selected insertion-associated genes |
|---|---|
T-ALL | ABL, ETO2, IKZF1, IL6-RB, LMO2, MLLT1, PIM1, RUNX1, TAL1 |
Breast | BCR, CCND1, FGFR1, KLF4, RUNX1 |
Neuroblastoma | ETV6, FOXO1, MYCN |
Lung | ASXL1, EML4, MYC, NF2 |
Colorectal | ATM, AXIN2, CASP8, ERG, MSH2, PDGFB, RUNX1, TCF3 |
Melanoma | AXIN1, BCL2, CCNE1, MYC, SS18L1, STAT3, U2AF1 |
Glioblastoma | ERG, EXT1, SND1 |
B cell lymphoma | ABL, BCL11A, BCL2, CASP8, CD79A, JAK2, LYL1, MSH2, PIM1, POU2AF1, RUNX1, TAL2, TNFAIP3 |
Pancreatic | ATM |
