Figure 3: Electron density map around the bound NADP+ in the Syn BVR.

(a) An omit Fo–Fc difference map for NADP+ contoured at 2.0 σ (cyan) is overlaid on stick models of Syn BVR and the bound NADP+. Dashed lines indicate hydrogen bonds, and distances are represented in angstrom units. (b) Structural rearrangements in the active site upon NADP+ binding. The structures of the apo-form (teal green) and NADP+-bound form (light green) are superposed.