Figure 5: The binding modes of the BVs and NADP⁺ in Syn BVR.

(a) Stereo view of the electron density map around the bound two BVs and NADP⁺ in the Syn BVR. An omit F_o–F_c difference map for BVs (blue and salmon pink) and NADP⁺ (cyan) contoured at 2.0 σ is overlaid on the stick models of the bound BVs and the bound NADP⁺. The view direction is same as in right panel in Fig. 2. (b) The environment around the bound two BVs in the Syn BVR. The bound BVs, NADP⁺ and the residues involved in the BV binding are shown with the stick. Dashed lines indicate hydrogen bonds.