Figure 5: Gained enhancer loci show chromatin marks of poised and primed enhancers in normal colon. | Nature Communications

Figure 5: Gained enhancer loci show chromatin marks of poised and primed enhancers in normal colon.

From: Hotspots of aberrant enhancer activity punctuate the colorectal cancer epigenome

Figure 5

(a) Bar plot of proportions of gained VELs that in normal crypt were enriched for H3K4me1, H3K27me3, or both marks. **χ2 P<0.0005. (b) Normalized H3K27me3, H3K27ac and H3K4me1 ChIP-seq profiles at the ARHGAP23 locus. Red bars (top) denote recurrent gained VELs present in 10 or more CRC cell lines (G10+).

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