Figure 1: Structures of sansanmycins A-C (1–3), synthetic dihydrosansanmycins A–C (4–6) and inhibitory activity against Mtb H37Rv. | Nature Communications

Figure 1: Structures of sansanmycins A-C (1–3), synthetic dihydrosansanmycins A–C (4–6) and inhibitory activity against Mtb H37Rv.

From: Sansanmycin natural product analogues as potent and selective anti-mycobacterials that inhibit lipid I biosynthesis

Figure 1

MIC values of isolated sansanmycins A–C (1–3) were previously reported by Xie et al.14,15 MIC50 values of 4–6 represent the average of two independent experiments, each performed in triplicate; positive controls RIF: MIC50=0.006±0.002 μM; INH: MIC50=0.025±0.005 μM; MIC50 (HEK293) for 4–6>200 μM.

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