Table 1 List of significant higher level or lower level miRNAs presented in the tumour exosomes (fold change).

Higher in tumour exo	Primary cancer/Naïve (log2)	Metast/Primary cancer (log2)	Lower in tumour exo	Primary cancer/Naïve (log2)	Metast/Primary cancer (log2)
mmu-miR-10a-5p	2.17	5.22	mmu-miR-423-5p	−2.44	−10.21
mmu-miR-126a-3p	6.21	4.76	mmu-miR-301a-3p	−3.11	−10.04
mmu-miR-22-3p	8.01	4.19	mmu-miR-33-5p	−5.73	−7.22
mmu-miR-192-5p	4.11	4.11	mmu-miR-9-5p	−1.93	−5.92
mmu-miR-339-5p	4.51	4.01	mmu-miR-151-5p	−3.75	−5.20
mmu-miR-148a-3p	8.59	3.94	mmu-miR-196b-5p	−3.51	−5.05
mmu-miR-193a-3p	5.24	3.75	mmu-miR-147-3p	−3.83	−5.03
mmu-miR-30b-5p	2.73	3.74	mmu-let-7i-5p	−2.02	−4.99
mmu-miR-200b-5p	1.94	3.34	mmu-miR-1195	−2.30	−4.97
mmu-miR-677-5p	2.31	3.17	mmu-miR-96-5p	−3.41	−4.62
mmu-miR-154-3p	1.72	2.96	mmu-miR-669b-5p	−2.15	−4.60
mmu-miR-678	3.02	2.79	mmu-miR-380-3p	−2.36	−4.17
mmu-miR-222-3p	2.59	2.57	mmu-miR-196a-5p	−5.16	−4.02
mmu-miR-203-3p	6.86	2.52	mmu-miR-375-3p	−2.74	−3.99
mmu-miR-331-3p	3.13	2.44	mmu-miR-181d-5p	−3.32	−3.90
mmu-miR-714	12.01	2.25	mmu-miR-672-5p	−2.58	−3.74
mmu-miR-883b-3p	1.84	1.94	mmu-miR-654-3p	−2.43	−3.74
			mmu-miR-1199-5p	−1.74	−3.49
			mmu-miR-683	−1.80	−3.43
			mmu-miR-882	−1.94	−3.35
			mmu-miR-875-3p	−1.89	−3.29
			mmu-miR-711	−1.87	−3.20
			mmu-miR-182-5p	−2.45	−3.15
			mmu-miR-466f-5p	−2.23	−3.13
			mmu-miR-764-3p	−3.50	−2.85
			mmu-miR-504-5p	−2.16	−2.62
			mmu-miR-17-5p	−4.07	−2.61
			mmu-miR-1892	−1.38	−2.57
			mmu-miR-205-5p	−4.53	−2.51
			mmu-miR-146b-5p	−1.79	−2.46
			mmu-miR-301b-3p	−2.90	−2.16
			mmu-miR-15b-5p	−4.14	−1.92
			mmu-miR-450b-3p	−3.68	−1.74

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