Figure 10: Tunnel pathway comparison between opsin and A2AR.
From: Membrane cholesterol access into a G-protein-coupled receptor

Gateways and tunnel pathways for (a) the high-resolution structure opsin (3CAP)—red surface and (b) the simulated A2AR (150 ns)—yellow surface computed using the Caver software49. Top: view from the membrane side, bottom: view from the extracellular side showing omitting gateway 3 for clarity in the A2AR.