Figure 1: TEs enriched for multiple pluripotency TF-binding sites.
From: Functional cis-regulatory modules encoded by mouse-specific endogenous retrovirus
(a) Upper panel: percentage of ChIP-seq peaks for each of the five pluripotency TFs, in TEs (red pie in chart). Lower panel: proportion of TEs bound by each TF, categorized by TE classes. ‘Background’ represents the distribution of TEs in the genome. (b) Proportion of TEs bound by one to five pluripotency TFs, categorized by TE classes. ‘Background’ represents the distribution of TEs in the genome. (c) Left panel: enrichment score (log odd ratio; y axis) of various number TFs’ ChIP-seq peaks (x axis) in individual TE subfamilies (each dot). (d) Enrichment (log odds ratio; y axis) of clusters of TF-binding motifs in TE subfamilies that were enriched for multiple TF ChIP-seq peaks, categorized by the number of TFs with motifs in the TE (x axis).
