Figure 7: Frequency-dependent entrainment of neonatal prelimbic cortex in response to layer-specific optogenetic activation in vivo. | Nature Communications

Figure 7: Frequency-dependent entrainment of neonatal prelimbic cortex in response to layer-specific optogenetic activation in vivo.

From: Layer-specific optogenetic activation of pyramidal neurons causes beta–gamma entrainment of neonatal networks

Figure 7

(a) Colour-coded images displaying the baseline normalized (pre, 1.5 s) coherence (mean and s.e.m.) between light-stimulated reference recording site in layer II/III (marked by X) and all other sites covering the PL depth during the first half (1.5 s), the second half (1.5 s) and after (post, 1.5 s) ramp stimulus. The coherence was calculated for theta (θ, 4–12 Hz, top), beta (β, 12–30 Hz, middle) and gamma (γ, 30–100 Hz, bottom) frequency bands and values were averaged (n=11 pups). (b) Same as (a) for layer V/VI-expressing P8–10 mice (n=6 pups). Reference recording site was located in the light-stimulated layer V/VI (marked by X). Blue arrows indicate the position of the light fibre. *P<0.05, **P<0.01 and ***P<0.001, two-sided t-tests.

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