Figure 7: mRNA stability in the presence of AN3661. | Nature Communications

Figure 7: mRNA stability in the presence of AN3661.

From: A potent antimalarial benzoxaborole targets a Plasmodium falciparum cleavage and polyadenylation specificity factor homologue

Figure 7

Northern blots shown are of parasite lines labelled as defined in Figs 3 and 4 (a–i) that were treated for 4 h with DMSO (untreated), actinomycin D, AN3661, artemisinin or chloroquine. RNA was then processed and the transcripts for purine nucleoside phosphorylase (PNP), 1-cys peroxiredoxin (1-CysPxn) and FP2 were detected and imaged as described in ‘Methods’ section. Levels of 28S rRNA were examined as a loading control. The figure shows results from a single experiment. Two additional experiments yielded the same results.

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