Figure 7: Global gene expression profiling of hiPanIN clones reveals their molecular similarities with native PanIN and PDA. | Nature Communications

Figure 7: Global gene expression profiling of hiPanIN clones reveals their molecular similarities with native PanIN and PDA.

From: Reconstituting development of pancreatic intraepithelial neoplasia from primary human pancreas duct cells

Figure 7

(a) RNAseq data presented as a hierarchically clustered heatmap. (b) Gene set enrichment analysis on RNAseq data with genesets compiled with publically available PDA and PanIN microarray data. NES, normalized enrichment score; p-val, nominal P value; q-val, false discovery rate q-value. (c) NMU immunohistochemical analyses on tissues with various pancreatic lesions. Results are representative of three to six independent experiments. Scale bars, 200 μm.

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