Table 3 Univariate and multivariate proportional hazards analyses of mortality in breast cancer patients according to MCT2 expression levels.

From: Adipocytes promote malignant growth of breast tumours with monocarboxylate transporter 2 expression via β-hydroxybutyrate

Variables

Univariate HR (95% CI)

P value

Multivariate HR (95% CI)

P value

MCT2 high-risk group (versus low-risk group)

2.22 (1.03–4.82)

0.043

3.59 (1.28–10.08)

0.016

Age (≥48 years old)*

0.76 (0.37–1.53)

0.440

0.47 (0.19–1.17

0.107

Tumour size (>2 cm)

4.83 (1.16–20.09)

0.031

4.00 (0.49–32.70)

0.199

Lymph-node status (per grade)†

2.36 (1.38–4.04)

0.002

3.87 (1.77–8.45)

0.001

Grade (per grade)

0.60 (0.31–1.16)

0.134

1.09 (0.51–2.34)

0.823

Estrogen-receptor positive stain (versus negative group)

0.40 (0.19–0.81)

0.012

0.10 (0.04–0.29)

<0.0001

  1. CI, confidence interval; HR, hazard ratio. Bold entries indicate P value <0.05.
  2. *Median of age: 48 years old.
  3. †Lymph-node positive, 0:0, 1:1∼3, 2: >4.
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