Figure 1: Distribution of DNMT3a protein in lumbar dorsal root ganglia of naive rats.

(a,b) DNMT3a is co-expressed exclusively with NeuN in cellular nuclei (a) and undetected in cellular nuclei (labelled by 4′, 6-diamidino-2-phenylindole (DAPI)) of glutamine synthetase (GS)-labelled cells (b). (c) Distribution of DNMT3a-positive somata: large, 30.2%; medium, 48.2%; small, 21.6%. (d–f) DNMT3a-positive neurons were labelled by calcitonin gene-related peptide (CGRP; d), isolectin B4 (IB4; e) or neurofilament-200 (NF200; f). n=5 rats. Scale bars, 50 μm.