Figure 4: Identification of a potential inhibitor-binding site in ZIKV NS5.
From: The structure of Zika virus NS5 reveals a conserved domain conformation
(a) Binding of a small-molecule inhibitor of DENV3 NS5 at its ‘N pocket’. The residues of DENV3 NS5 and small-molecule inhibitor are shown in blue and yellow sticks, respectively. The hydrogen bonding interactions are depicted as dashed lines. (b) The residues of ZIKV NS5 corresponding to the inhibitor binding site of DENV3 NS5 are shown in pink sticks.
