Figure 2: Overall and detailed view of the ZIKV NS5 RdRp.
From: Crystal structure of Zika virus NS5 RNA-dependent RNA polymerase
(a) General view of the ZIKV NS5 RdRp coloured by thumb (green), fingers (yellow) and palm (purple) domains. Zinc atoms are coloured as red spheres. (b) Details of the fingers domain zinc-binding site shows main coordinating amino acids (E439, H443, C448 and C451) depicted as sticks. (c) Details of the thumb domain zinc-binding site shows main coordinating amino acids (H714, C730 and C894) depicted as sticks. Blue mesh represents the 2Fo-Fc with 1.0 sigma.
