Table 1 Laboratory parameters of patients.
Parameter | Patient 1 | Patient 2 | Patient 3 |
|---|---|---|---|
Haemoglobin (g l−1) | 103 (115–180) | 103 (110–140) | 122 (120–160) |
White blood cells (× 109 l−1) | 29 (5.0–20.0) | 23.5 (5.0–12.0) | 13.8 (4.0–10.0) |
Platelets (× 109 l−1) | 18 (150–400) | 345 (150–400) | 335 (150–400) |
Lymphocytes (× 109 l−1) | 11.9 (2.0–17.0) | 17.4 (4.0–10.5) | 4.18 (1.5–7.0) |
Eosinophils (× 109 l−1) | 3.5 (0.7–1.0) | 2.82 (0.05–0.70) | 3.14 (0.02–0.05) |
ESR (mm h−1) | 102 (1–10) | 55 (1–10) | 35 (1–10) |
Markers | |||
 CD3 (cells μl−1) | 1,409 (900–4,500) | 5,609 (2,400–6,900) | 1,484 (700–4,200) |
 CD4 (cells μl−1) | 914 (500–2,400) | 4,487 (1,400–5,100) | 992 (300–2,000) |
 CD8 (cells μl−1) | 122 (300–1,600) | 1,596 (600–2,200) | 431 (300–1,800) |
 CD19 (cells μl−1) | 5,910 (200–2,100) | 8,469 (700–2,500) | 1,545 (200–1,600) |
 CD56 (cells μl−1) | 251 (100–1,000) | 932 (100–1,000) | 987 (90–900) |
Mitogenic responses (stimulation index percent of control) | |||
 PHA | Normal (>50) | Normal (>50) | Normal (>50) |
 αCD3 | Normal (>50) | Normal (>50) | Normal (>50) |
Immunoglobulins | |||
 IgG (g l−1) | 11.6 (4.5–14.3) | 9.7 (1.1–7.0) | 11.9 (5.4–13.6) |
 IgA (g l−1) | 6.1 (0.2–1.0) | 5.1 (0.0–0.3) | 4.4 (0.5–2.2) |
 IgM (g l−1) | 0.4 (0.2–1.8) | 1.0 (0.2–0.9) | 0.8 (0.4–1.5) |
 IgE (IU ml−1) | 1,366 (<163) | 414 (<25) | 1,799 (<90) |
Specific antibodies | |||
 Anti-tetanus (IU ml−1) | 1.73 (>0.1) | >7.00 (>0.1) | 1.21 (>0.1) |
 Anti-pneumococcus (mg l−1) | >270 | ND | ND |
 Isohemagglutinin | αA: 1:64 (>1:8) | ND | αA: 1:16 (>1:8) |
|  | αB: 1:64 (>1:8) |  | αB: 1:8 (>1:8) |
Auto-antibodies | |||
 ANA | 1:160 (Neg) | 1:160 (Neg) | Neg (Neg) |
 ANCA | Pos (Neg) | Pos (Neg) | Pos (Neg) |
 TRECS (copy no/3 μl) | >2,000 (>400) | 1,239.5 (>400) | 1,636 (>400) |
