Figure 5: Distribution of average CNV lesion grades.
From: Long-acting protein drugs for the treatment of ocular diseases
In the cohort of monkeys that were imaged 22 days post dosing, eyes that received ranibizumab had six grade IV lesions, whereas none of the eyes that received LAVA1 had grade IV lesions (all lesions were grade I). In the cohort of monkeys that were imaged 49 days post dosing, eyes that received ranibizumab had 18 grade IV lesions, whereas eyes that received LAVA1 had 13 grade IV lesions.
