Figure 2: Genome-wide meta-analysis for RHD susceptibility.

For each variant, the negative common logarithm of the P value from an inverse-variance weighted fixed-effects meta-analysis is plotted against genomic position. The blue horizontal line indicates suggestive significance (FE meta-analysis, P=10−5) and the red horizontal line indicates genome-wide significance (FE meta-analysis, P=5 × 10−8).