Figure 2: Forest plot for novel and GxSMK loci stratified by smoking status. | Nature Communications

Figure 2: Forest plot for novel and GxSMK loci stratified by smoking status.

From: Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits

Figure 2

Estimated effects (β±95% CI) for smokers (N up to 51,080) and nonsmokers (N up to 190,178 ) per risk allele for (a) BMI, (b) WCadjBMI and (c) WHRadjBMI for novel loci from Approaches 1 and 2 (SNPadjSMK and SNPjoint, respectively) and all loci from Approaches 3 and 4 (SNPint and SNPscreen) identified in the primary meta-analyses. Loci are ordered by greater magnitude of effect in smokers compared to nonsmokers and labelled with the nearest gene. For the locus near TMEM38B, rs9409082 was used for effect estimates in this plot. (¥loci identified for Approach 4, *loci identified for Approach 3).

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