Figure 5: Inhibition of H2O2-induced TLCL peroxidation.
From: A mitochondria-targeted inhibitor of cytochrome c peroxidase mitigates radiation-induced death
(a) Typical ESI mass spectra of doubly charged molecular ions of non-oxidized TLCL and TLCL oxidized by CL/cyt c and H2O2. Mass-to-charge (m/z; negative MS mode) values of 723.5 and 731.5, 739.5, 747.5, 755.5, 763.5, 771.5 and 779.5 were assigned to molecular clusters of non-oxidized TLCL and TLCL enriched with 1–7 oxygen atoms, respectively. (b) Quantitative assessment of TLCL and its oxidation products by ESI-MS. Data are means±s.d., n=3, *P<0.05 (ANOVA) versus TLCL/cyt c/H2O2.
