Figure 4: Cold exposure induces HDL lipidome remodelling in humans.
From: Thermogenic adipocytes promote HDL turnover and reverse cholesterol transport
Plasma lipoprotein profiles determined by FPLC in (a) 9 lean and (b) 10 obese humans before and after 2 day-treatment with cold. Changes in (c) PC, (d) lyso-PC and (e) CE species in HDL from cold-treated individuals relative to their baseline levels are represented as per cent weight changes of total lipid class. Calculated values are mean±s.e.m. (n=9–10 per group). Post hoc correction for multiple testing was performed using the Benjamini–Hochberg method for the number of lipids shown.*P<0.05, **P<0.01, versus mock (Student’s t-test).
