Figure 5: Models of MERS-CoV and SARS-CoV S trimers bound to their receptors. | Nature Communications

Figure 5: Models of MERS-CoV and SARS-CoV S trimers bound to their receptors.

From: Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains

Figure 5

The models were built by superimposition of the S trimer structures with the RBD-receptor complex structures through the RBD domains. The MERS-CoV S trimer can cross-link the dimeric CD26 receptor during the binding (a), whereas the SARS-CoV S trimer can bind one monomeric ACE2 receptor (b).

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