Figure 1: Preparation and characteristics of GNC–siRNA complex.
From: Gold nanoclusters-assisted delivery of NGF siRNA for effective treatment of pancreatic cancer
(a) Molecular structure of GSH and CR9. (b) Scheme of the preparation of positively charged GNCs. (c) Scheme of the preparation of GNC–siRNA complex. The negatively charged siRNA was condensed onto cationic GNCs by electrostatic interaction. (d) The appearance of GNC solution. (e) Excitation and emission spectrum of GNCs. (f) Surface charge of GNCs. Mean±s.d. (n=16). (g) CryoTEM images of GNCs. (h) Diameter of the prepared GNCs. Mean±s.d. (n=120). (i) CryoTEM images of the GNC–siRNA complex. (j) Diameter of the GNC–siRNA complex. Mean±s.d. (n=30). Scale bars, 10 nm.
