Figure 8: A model of water-reward LTM and STM brain circuits.
From: Neural circuits for long-term water-reward memory processing in thirsty Drosophila
LTM requires reinforcement from ∼13 dopaminergic PAM-β′1 neurons that innervate a restricted zone of the MB β′ lobe. This is different from the STM-reinforcing dopaminergic neurons (PAM-γ4) that innervate the MB γ lobe. After association, the LTM consolidation requires the synaptic output in α′β′ neurons, whereas the LTM retrieval requires the output in αβ and γ neurons. Finally, the LTM is read out from the αβ and γ neurons via cholinergic MB-V3 neurons and glutamatergic MB-M6 neurons, respectively.
