Figure 4: NOESY spectrum of the VK34 tetramer.
From: Tetrahelical structural family adopted by AGCGA-rich regulatory DNA regions
(a) H2′/H2″-aromatic region. The sequential walks from G1 to A4 and C10 to G15 are depicted in blue. The sequential walk from G5 to G9 is depicted in magenta. The NOE contacts between A4 and A12 residues as well as A8 H2′-A8 H2 and A8 H2″-A8 H2 NOE contacts are depicted in red. (b) Sugar-imino region. The dashed lines correspond to chemical shifts of imino proton resonances of G3, G6, G7, G9 and G11 residues. (c) imino-aromatic region. (d) imino-imino region. NOE contacts with fingerprints characteristic only for the VK34 tetramer are depicted in magenta. NOE contacts that have fingerprints similar to the VK34 dimer are depicted in blue. NOESY spectrum was recorded at 1.0 mM oligonucleotide concentration per strand, 150 mM NaCl, pH 6.0, 0 °C and at mixing time of 150 ms.
