Figure 5: Schematic representation and the lowest-energy structure of the VK34 tetramer.
From: Tetrahelical structural family adopted by AGCGA-rich regulatory DNA regions
(a) Schematic representation of the VK34 tetramer. The asterisk marks the intersection point of three C2 rotational axes of symmetry. (b) Cartoon representation of the overall lowest-energy structure (PDB ID: 5M2L). (c) G7-A8-G7-A8, G6-G9-G6-G9 and G5-C10-G5-C10 quartets. (d) View into a narrow groove of the central region. (e) Two stacked GAGA-quartets with C2 rotational axes of symmetry. The guanine bases in anti orientation are coloured in blue, guanines in syn orientation in cyan, adenine in red and cytosine in orange. Hydrogen bonds are shown as dotted black lines. The dashed boxes in a highlight parts of the structure that adopt similar structural arrangements as in the dimeric structure.
