Figure 2: Association of psoriasis susceptibility with disease risk. | Nature Communications

Figure 2: Association of psoriasis susceptibility with disease risk.

From: Large scale meta-analysis characterizes genetic architecture for common psoriasis associated variants

Figure 2

(a) The effect size (odds ratio, OR) of the risk allele is plotted against the minor allele frequency of the signal among all susceptibility loci. (b) True positive rate versus false positive rate for using genetic risk score to distinguish psoriasis versus control samples. Blue line shows the averaged results among the different cohorts (grey), and the s.e. bars are also shown. (c) The median age-at-onset of psoriasis is plotted against different percentile bins (every 2%) of genetic risk scores for all loci (blue) or all loci without MHC (red).

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