Figure 10: Relative mRNA expression of specific Mmps and Tace after administration of peptide MMP inhibitors. | Nature Communications

Figure 10: Relative mRNA expression of specific Mmps and Tace after administration of peptide MMP inhibitors.

From: Inhibition of gelatinase B/MMP-9 does not attenuate colitis in murine models of inflammatory bowel disease

Figure 10

Relative mRNA expression measured in colonic mouse tissue after a therapeutic injection scheme (n=16) (a), a prophylactic injection scheme (n=23) (b) and continuous osmotic pump delivery (n=22) (c) of peptide inhibitors A and B. Expression levels were normalized to the control condition (water+saline) and 18S with the use of the 2-delta delta CT method48. Mean values with s.e.m. are shown. Statistical analyses were performed with Mann–Whitney U tests (*P<0.05, **P≤0.01; NS, not significant). Colour codes are similar as in Figs 8 and 9.

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