Figure 5: TWEAK synergizes with IL-13 and IL-17A to induce chemokines in human keratinocytes.
From: TWEAK mediates inflammation in experimental atopic dermatitis and psoriasis

(a) Basal surface expression of Fn14 (line) on NHEK cells relative to Isotype staining (grey). (b,c) NHEK cells were stimulated for 48 h with rTWEAK, rIL-13, rIL-17 or their combination. mRNA expression of indicated chemokines was assessed relative to GAPDH. Means of triplicate cultures with standard deviations. Values were compared using Student’s t-test. One out of three independent experiments.