Figure 1: Htt exon1 sequence and domain structure. | Nature Communications

Figure 1: Htt exon1 sequence and domain structure.

From: Fibril polymorphism affects immobilized non-amyloid flanking domains of huntingtin exon1 rather than its polyglutamine core

Figure 1

(a) The domain structure and sequence of htt exon1 is shown at the top. The locations of PTMs, as well as the binding sites of various antibodies and other htt-binding proteins are indicated25,26,27,28,29,30,31,32,33,34,58. (b) Design of previously studied13 HNTF peptide httNTQ30P10K2. (c) Design of the MBP fusion protein, with the sequence of the Factor Xa cleavage site in the linker shown below.

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