Figure 2: β-Catenin/BCL9L/TCF4 signalling targets the GCM1/syncytin pathway in BeWo cells.
From: Identification of a link between Wnt/β-catenin signalling and the cell fusion pathway
qRT–PCR analysis of the effect of BCL9L, β-catenin or TCF4 knockdown on FK-induced GCM1, syncytin-1 and syncytin-2 expression. Values were normalized by GAPDH expression level and are shown as fold increase against mock control. Si (gene symbol) -1 and -2 denote siRNAs targeting different sites of the mRNA. Values are shown as mean±s.e.m. **P<0.01; ***P<0.001. N=4. Statistical tests were performed using unpaired two-tailed t-tests. Open bars, control; closed bars, FK.
