Figure 2: Putative functional somatic mutations in thyroid tissues.
From: The genetic landscape of benign thyroid nodules revealed by whole exome and transcriptome sequencing
(a) Landscape of significantly mutated gene and genes previously associated with PTC in thyroid tissues. The frequency of mutation in each sample type was indicated in the left histogram. (b) Schematic representation of mutations in SPOP, EZH1 and ZNF148. Conserved domains were indicated as boxes. Somatic mutations detected in our cohort were indicated in the upper. Somatic mutations of these three genes in expanding 231 patients were indicated in grey (bottom).
