Figure 2: Indentifying miRNAs regulating cancer cell migration and invasion.
From: Genome-wide functional screening of miR-23b as a pleiotropic modulator suppressing cancer metastasis
(a) Pie diagram showing the distribution of the migratory miRNAs. The 2% false positives are mainly due to proliferation. (b) General regulation of miRNA on the migratory behaviours. Noticeably, no miRNAs exhibited a contrasting migratory regulation capacity. Transwell cell migration assay is used here. (c) Summary of the miRNA functional screen. MiRNAs previously reported to regulate cell migration, invasion or apoptosis are highlighted in blue.
