Table 1 miRNAs capable of downregulating cell migration, invasion and inducing apoptosis.

From: Genome-wide functional screening of miR-23b as a pleiotropic modulator suppressing cancer metastasis

No.

miRNA

Migration

Invasion

Apoptosis

Total scores

 1

miR-22

Inhibit**

Inhibit*

Promote**

5*

 2

miR-101

Inhibit**

Inhibit*

Promote**

5*

 3

miR-128

Inhibit*

Inhibit***

Promote**

6*

 4

miR-138

Inhibit**

Inhibit***

Promote*

6*

 5

miR-143

Inhibit***

Inhibit**

Promote**

7*

 6

miR-145

Inhibit***

Inhibit**

Promote**

7*

 7

miR-185

Inhibit***

Inhibit***

Promote*

7*

 8

miR-190

Inhibit**

Inhibit**

Promote*

5*

 9

miR-206

Inhibit***

Inhibit**

Promote*

6*

10

miR-421

Inhibit**

Inhibit**

Promote*

5*

11

miR-433

Inhibit*

Inhibit*

Promote*

3*

12

miR-451

Inhibit***

Inhibit***

Promote*

7*

13

miR-497

Inhibit**

Inhibit**

Promote*

5*

14

miR-559

Inhibit*

Inhibit*

Promote*

3*

15

miR-1181

Inhibit*

Inhibit***

Promote*

5*

16

miR-1201

Inhibit*

Inhibit**

Promote*

4*

17

miR-1266

Inhibit*

Inhibit***

Promote*

5*

18

miR-1469

Inhibit**

Inhibit***

Promote*

6*

19

miR-1979

Inhibit*

Inhibit***

Promote*

5*

20

miR-1255a

Inhibit**

Inhibit***

Promote*

6*

21

miR-200a

Inhibit**

Inhibit**

Promote*

5*

22

miR-200b

Inhibit*

Inhibit**

Promote*

4*

23

miR-200c

Inhibit**

Inhibit**

Promote*

5*

24

miR-22*

Inhibit**

Inhibit**

Promote*

5*

25

miR-23b

Inhibit**

Inhibit***

Promote***

8*

26

miR-26a

Inhibit**

Inhibit*

Promote***

6*

27

miR-29a

Inhibit**

Inhibit*

Promote**

5*

28

miR-29a*

Inhibit*

Inhibit*

Promote*

3*

29

miR-29c

Inhibit**

Inhibit**

Promote**

6*

30

miR-33b

Inhibit*

Inhibit**

Promote*

4*

31

miR-34a

Inhibit**

Inhibit*

Promote**

5*

32

miR-34b

Inhibit*

Inhibit*

Promote*

3*

33

miR-34c-5p

Inhibit*

Inhibit*

Promote**

4*

34

miR-593*

Inhibit***

Inhibit***

Promote*

7*

35

miR-let-7a

Inhibit**

Inhibit**

Promote**

6*

36

miR-let-7b

Inhibit*

Inhibit**

Promote**

5*

  1. Migration and Invasion, — no significance; *15–30%; **30–60%; ***>60%. Apoptosis, *25–50%; **50–100%; ***>100%. All data presented here stands for the decrement or increment compared with negative control (NC) experimental data (scramble siRNA): first normalized to NC data, and subtracted to 100%.
  2. Total score= Star no. of migration+Star no. of invasion+Star no. of apoptosis.
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