Figure 6: DNAM-1+ and DNAM-1− NK cells respond to receptor crosslinking.
From: Expression of CD226 is associated to but not required for NK cell education
(a) Expression of IFN-γ and CD107a on DNAM-1+ and DNAM-1− Ly49A SP NK cells from a Dd-transgenic mouse on Kb−/−Db−/− background (Kb−/−Db−/−Dd+/+), after crosslinking with anti-NK1.1, one representative plot shown. (b) Frequency of IFN-γ+ NK cells on Ly49r SP subsets (n=6, 3 experiments). (c) Expression of IFN-γ and CD107a on DNAM-1+ and DNAM-1− Ly49C-SP NK cells from a Db−/− mouse (Kb+/+Db−/−) after crosslinking with anti-NK1.1, one representative plot shown. (d) Frequency of IFN-γ+ NK cells on Ly49r SP subsets (n=6, 3 experiments).
