Figure 3: Bru-Seq data show downregulation at 4 h after DSB induction. | Nature Communications

Figure 3: Bru-Seq data show downregulation at 4 h after DSB induction.

From: A damaged genome’s transcriptional landscape through multilayered expression profiling around in situ-mapped DNA double-strand breaks

Figure 3

(a) Boxplot representing log2 of the fold change of expression for genes (n=196) with cut AsiSI sites at different time points (30 min, 1, 2 and 4 h) after DSB induction. (b) Coverage profile plot representing the RPM of Bru-seq reads in induced (blue) and uninduced (red) samples for each genebody region. TES, transcription end site; TSS, transcription start site. Bold lines represent mean values, whereas semi-transparent shades around the mean curves represent the s.e.m. across the regions.

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