Figure 9: Model for regulation of mVEGFR1 stability in endothelial cells.
From: Dynamic alterations in decoy VEGF receptor-1 stability regulate angiogenesis
mVEGFR1 is normally (left) highly stable and slowly recycled to and from the surface via Rab11a, requiring Rab27a and DHHC3 for palmitoylation; reduced Rab27a levels (right) destabilize mVEGFR1 via reduced palmitoylation, leading to increased signalling through VEGFR2.
