Table 1 Overview over the genes included in the array.
Genes included | No. | |
|---|---|---|
GPCRs | – Adrenergic: Adra1a, Adra1b, Adra1d, Adra2c, Adrb1, Adrab2– Chemokine: Ccbp2/Ackr2, Ccr10, Ccr1, Ccr2, Ccr3, Ccr4, Ccr5, Ccr6, Ccr7, Ccr8, Ccr9, Ccrl1, Ccrl2, Cx3cr1, Cxcr1, Cxcr2, Cxcr3, Cxcr4, Cxcr5, Cxcr6, Cxcr7, Xcr1– Lysophospholipid: Lpar1, Lpar2, Lpar3, Lpar4, Lpar6 , S1pr1, S1pr2 , S1pr3, S1pr4– Miscellaneous: Adcyap1r1, Adora1, Adora2a, Agtr1a, Aplnr , Avpr1a, Bdkrb1 , Bdkrb2, C3ar1, C5ar1, Calcrl, Chrm2, Chrm3, Cmklr1, Cnr2, Crhr2, Cysltr1, Ednra, Ednrb, Fpr1, Fpr2, Gabbr1, Glp1r, Glp2r, Hrh1 , Hrh2, Htr1b , Htr2a, Niacr1 , Npy1r, Olfr78, Prokr1, Ptafr, Pth1r, Smo, Sstr4 , Sucnr1, Tas2r126, Tas2r135, Tas2r143 , Vipr1, Vipr2– Orphan: Cd97, Celsr2, Darc, Eltd1, Emr1, Emr4, Gpr107, Gpr108, Gpr111, Gpr114, Gpr116, Gpr124, Gpr125, Gpr126, Gpr132, Gpr133, Gpr137, Gpr137b, Gpr146 , Gpr153, Gpr171, Gpr174 , Gpr176, Gpr18, Gpr182 , Gpr183, Gpr19, Gpr21, Gpr30, Gpr34, Gpr35 Gpr39, Gpr4, Gpr52 , Gpr56, Gpr63, Gpr64, Gpr65, Gpr83, Gpr97, Gprc5a, Gprc5b, Gprc5c, Lgr4, Lgr5, Lgr6, Lphn1, Lphn2, Lphn3, Mrgprf, Mrgprh– Prostanoid: Ptger1, Ptger2, Ptger3, Ptger4, Ptgfr, Ptgir, Tbxa2r– Protease: F2r, F2rl1, F2rl2, F2rl3– Purinergic: P2ry1, P2ry10, P2ry12, P2ry13, P2ry14, P2ry2, P2ry6 | 154 (inton-span-ning: 132) |
Cell identity | eGFP, Myh11 (smooth muscle), Cdh1 (epithelial), Cdh5 (endothelial), Ptprc (leukocyte), Itgam (myeloid), Ly6g (neutrophil), Cd19 (B lymphocyte), Cd4 (CD4 T lymphocyte), Cd8 (CD8 T lymphocyte), Lyve1 (lymphatic EC), Cspg4 (pericyte), Tnni2 (skeletal muscle) | 13 |
Cell function | – Cell activation/differentiation: Cd25, Cd44, H2-Ab1, Pecam1, Acta2, Edn1, Dll4, Sele, Smtn, Icam1, Vcam1, Col1a2, Col3a1– Cytokines/Growth factors: Csf2,Csf2rb, Kdr, Pdgfb, Tgfb1, Tnf, Ifng, IL10, Il17a, Il1b, Il2, Il6– Transcription factors: Rorc, Tbx21, Mki67, Egr1, Fos, Hif1a, Hey2, Klf2– Reference genes: Actb, Gapdh, Hprt | 36 |
