Figure 4: Results/summary of the navigation of the model reaction network using the RSI algorithm.
From: An autonomous organic reaction search engine for chemical reactivity
(a) Schematic of the organic reaction search engine used for the navigation of the 4 × 4 × 4 chemical network. Each reactant is associated with a syringe pump and connected to the flow reactor of the first, second or third step, using a multi-way connector. After each reaction step, the RSI for the pathway screened is calculated and used to continue the reaction network navigation. (b) Illustration of the reaction network navigation using the RSI showing the navigation of the III generation compounds 8a–d synthesis and the selection of the pathway related to compound 8a using the RSI.
