Figure 5: ILC2 alter the plaque composition.
From: Type-2 innate lymphoid cells control the development of atherosclerosis in mice
Phenotypic changes in the enlarged plaque (a) favour increased MOMA2+. Proportional and numerical decrease in Arginase1 (Arg1) expressing cells (b). Flow cytometry of CD11b+ F4/80+ aorta resident macrophages indicated bias towards reduced Arg1 and increased iNOS expression (c). Representative micrographs of MOMA2+ staining are shown. Graph data points represent individual mice and statistical significance was determined by Mann–Whitney U-test. Scale bars: 270 μm.
