Table 3 Association between polygenic risk scores and age at first child.
From: Reproductive fitness and genetic risk of psychiatric disorders in the general population
Total sample | Males | Females | ||||
|---|---|---|---|---|---|---|
Polygenic score | P value | Beta (CI) | P value | Beta (CI) | P value | Beta (CI) |
ADHD | 0.0003 | −0.59 (−0.92, −0.26) | 0.07 | −0.48 (−0.99, −0.03) | 0.0005 | −0.71 (−1.12, −0.31) |
Autism | 0.0004 | 0.97 (0.43, 1.51) | 0.03 | 0.91 (0.08, 1.76) | 0.001 | 1.10 (0.45, 1.77) |
Bipolar disorder | 0.005 | 0.14 (0.04, 0.23) | 0.18 | 0.10 (−0.04, 0.25) | 0.007 | 0.16 (0.04 − 0.28) |
Major depression | 0.006 | −0.31 (−0.54, −0.09) | 0.71 | −0.06 (−0.42, 0.28) | 9.00E−05 | −0.56 (−0.84, −0.28) |
Schizophrenia | 0.07 | −0.02 (−0.05, 0.003) | 0.81 | −0.005 (−0.05, 0.04) | 0.02 | −0.04 (−0.07, −0.01) |
